Hydrocodone

Combination drugs: Lortab®, Tussionex®, Vicodin®, Vicoprofen®

Hydrocodone is a narcotic analgesic used in combination products to relieve mild to moderate pain and an antitussive agent to relieve cough and upper respiratory symptoms associated with allergy or cold.

Safetychecker Summary for Hydrocodone
(for details about the summarized interactions, read the full article)

Depletion or interference

None known

Side effect reduction/prevention

None known

Supportive interaction

None known

Reduced drug absorption/bioavailability

None known

Adverse interaction

None known

An asterisk (*) next to an item in the summary indicates that the interaction is supported only by weak, fragmentary, and/or contradictory scientific evidence.

Interactions with Foods and Other Compounds

Food
Hydrocodone may cause gastrointestinal (GI) upset. Hydrocodone-containing products may be taken with food to reduce or prevent GI upset.1 A common side effect of narcotic analgesics is constipation.2 Increasing dietary fiber (especially vegetables and whole-grain foods) and water intake can ease constipation.

Alcohol
Hydrocodone may cause drowsiness, dizziness, or blurred vision. Alcohol may intensify these effects and increase the risk of accidental injury.3 To prevent problems, people taking hydrocodone should avoid alcohol.

References:

1. Threlkeld DS, ed. Central Nervous System Drugs, Narcotic Agonist Analgesics. In Facts and Comparisons Drug Information. St. Louis, MO: Facts and Comparisons, Feb 1990, 242–3v.

2. Threlkeld DS, ed. Central Nervous System Drugs, Narcotic Agonist Analgesics. In Facts and Comparisons Drug Information. St. Louis, MO: Facts and Comparisons, Feb 1990, 242–3v.

3. Threlkeld DS, ed. Central Nervous System Drugs, Narcotic Agonist Analgesics. In Facts and Comparisons Drug Information. St. Louis, MO: Facts and Comparisons, Feb 1990, 242–3v.