Buspirone is used to treat anxiety disorders and less commonly to treat symptoms of premenstrual syndrome.
Safetychecker Summary
for Buspirone
(for details about the summarized interactions, read the full article)
 Avoid: Adverse interaction—Avoid these supplements
when taking this medication because taking them together may cause undesirable or dangerous
results. |
Kava |
| Depletion or interference |
None known |
| Side effect reduction/prevention |
None known |
| Supportive interaction |
None known |
| Reduced drug absorption/bioavailability |
None known |
An asterisk (*) next to an item in the summary indicates that the interaction is supported only by weak, fragmentary, and/or contradictory scientific evidence.
Interactions with Herbs
Kava (Piper
methysticum)
Kava is an herb used to treat anxiety disorder. Although no direct interactions have been
reported, buspirone should not be used together with kava unless with medical supervision.
Interactions with Foods and Other Compounds
Food
Food reduces metabolism of buspirone, increasing serum buspirone levels.1 Buspirone
should be taken at the same time each day, always with food or always without food.
Alcohol
Buspirone may cause drowsiness and dizziness.2 Alcohol may compound these effects
and increase the risk of accidental injury. To prevent problems, people taking buspirone
should avoid alcohol.
References:
1. Gammans RE, Mayol RF, LaBudde JA. Metabolism and disposition of buspirone. Am J Med 1986;80:41–51.
2. Threlkeld DS, ed. Central Nervous System Drugs, Antianxiety Agents, Miscellaneous Agents. In Facts and Comparisons Drug Information. St. Louis, MO: Facts and Comparisons, May 1990, 262–c.
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The information presented in Healthnotes is for informational purposes only. It is based on scientific studies (human, animal, or in vitro), clinical experience, or traditional usage as cited in each article. The results reported may not necessarily occur in all individuals. For many of the conditions discussed, treatment with prescription or over-the-counter medication is also available. Consult your doctor, practitioner, and/or pharmacist for any health problem and before using any supplements or before making any changes in prescribed medications. Information expires December 2003.